Thank you for stopping by Brennan Healthcare Consulting. I’m Ryan Brennan, a life‑long student of the med‑tech industry who has spent more than 20 years leading sales, marketing and clinical organizations for some of the world’s most innovative medical device and biotechnology companies. Over that time I’ve become known for scaling high‑growth teams, distilling complex technology into an impactful value proposition, honing the ideal customer profile, and building territories, quotas and commission structures that keep salespeople and health‑care providers (HCPs) aligned. I partner with start‑ups and established companies alike to turn visionary ideas into real health‑care solutions.

Bringing precision diagnostics to market at Previse

In 2023 I joined Previse as the head of business development to help bring the company’s groundbreaking tissue prognostic assay, Esopredict, to market. Esopredict is designed as a predictive test that evaluates the risk of esophageal cancer in patients with Barrett’s esophagus. As the company’s sole commercial leader, I was responsible for strategic planning, stakeholder outreach and market execution. My team’s efforts established Previse as a serious player in gastro‑intestinal diagnostics and helped pave the way for its acquisition by Castle Biosciences. I remain proud that our work brought a novel precision‑medicine solution to patients who urgently need more reliable prognostic tools.

Launching a U.S. presence for Creo Medical

Before Previse, I was the first U.S. employee at Creo Medical and spearheaded the company’s entry into the United States. Creo’s CROMA platform combines advanced bipolar radio‑frequency and microwave energy for the dissection, resection, ablation and haemostasis of diseased tissue. As President of U.S. Sales, Service and Commercial Operations, I built the sales and clinical teams from the ground up and oversaw the successful U.S. launch of the Speedboat Inject device, which has since been adopted by hospitals worldwide. The experience cemented my belief that strong commercial execution is essential to turning brilliant technology into broad clinical impact.

Driving interventional endoscopy growth at PENTAX Medical

From 2016 to 2020 I served as vice president of interventional endoscopy sales for PENTAX Medical, a company that has evolved from a century‑old manufacturer into a healthcare provider of cutting‑edge endoscopy solutions and is dedicated to addressing the challenges of healthcare professionals. When PENTAX acquired C2 Therapeutics and its cryo‑balloon ablation technology, I built the sales and clinical team from scratch, cultivating a highly collaborative user community of renowned interventional gastroenterologists. Working closely with these physicians, we generated robust clinical data and helped refine the product. After the acquisition, PENTAX retained my entire team and asked us to expand our scope by selling the company’s EUS and ERCP endoscopes in addition to the cryo‑balloon line. Under my leadership we operated like a “seal team six,” executing national sales strategies, building alliances with gastroenterologists and surgeons, and helping the organization transition from a product‑centric business to a solutions partner for physicians.

Championing plasma energy with Plasma Surgical

As vice president of U.S. sales at Plasma Surgical (2013–2014) I introduced surgeons to the PlasmaJet surgical system, which uses pure plasma energy to cut, vaporize, coagulate and dissect tissue with controlled depth and minimal thermal effect. The PlasmaJet enabled surgeons to perform both open and laparoscopic procedures without passing electrical current through the patient. I built a national sales team and worked closely with oncologic surgeons to position this technology as a new standard of care.

Advancing GERD therapy at Torax Medical

Following my time at Plasma Surgical I joined Torax Medical as a sales representative to introduce the LINX® Reflux Management System to gastrointestinal surgeons and gastroenterologists. LINX is a laparoscopic, fundic‑sparing anti‑reflux procedure in which a flexible ring of small magnets is placed around the lower esophageal sphincter; the magnets are precisely calibrated to keep the weak sphincter closed and prevent gastric reflux. Working alongside early adopters, I helped educate patients and physicians on this novel magnetic sphincter augmentation technology. Torax’s success eventually attracted the attention of Johnson & Johnson, which acquired the company after my tenure.

Record‑setting performance at Barrx Medical

I spent nearly six years at Barrx Medical (later acquired by Covidien/Medtronic), where I consistently ranked as the top‑performing sales representative. Barrx pioneered the radiofrequency ablation (RFA) system used to remove precancerous tissue in patients with Barrett’s esophagus. The technology uses heat to remove the diseased tissue while preserving the underlying healthy tissue and has been considered a safe and effective technique to treat Barrett’s esophagus. By working closely with gastroenterologists, I drove the highest utilization of Barrx’s Halo catheters in the country and delivered back‑to‑back Region of the Year awards for both the West and Mid‑Atlantic territories. Our CEO later cited this performance as a key factor in Covidien’s $425 million acquisition of the company.

Earlier roles and foundational experience

My early career provided a broad foundation in surgical devices. At Johnson & Johnson I honed my skills in territory management and collaboration. I then joined Intuitive Surgical as an area sales manager during the rapid adoption of the da Vinci robotic‑assisted surgery system; Intuitive’s mission is to advance minimally invasive care through robotic‑assisted surgery and bronchoscopy systems, helping physicians optimize care delivery and improve outcomes. The company’s relentless pursuit of integrated systems, software and education to keep hospitals at the forefront of minimally invasive care shaped my own customer‑centric philosophy.

I began my journey at Karl Storz Endoscopy, a family‑owned med‑tech firm founded in 1945 that has grown into an international leader in endoscopy with 13,000 products serving human and veterinary medicine across more than 40 countries. As a territory manager I carried the entire product line—integrated operating rooms, video systems, laparoscopic equipment and instruments for specialties ranging from ENT and urology to gynecology, orthopedics and more. By developing deep product knowledge and partnering with surgeons across these disciplines, I overachieved quota every year and laid the foundation for a career built on trust, precision and long‑term thinking in medical technology.

How I can help your organization

Across each of these roles I’ve been privileged to work with talented clinicians and entrepreneurs who share a commitment to improving patient outcomes. I believe the most effective commercial strategies begin with deep empathy for both physicians and patients. My consulting practice draws on this philosophy to help companies:

• Scale high‑growth teams: recruit and develop sales and clinical specialists who deliver value to customers.

• Craft and refine value propositions: translate complex science into clear benefits for HCPs and payers.

• Define the ideal customer profile: focus resources on the right physician segments and health systems.

• Design territories, quotas and incentive plans: align compensation with growth goals and encourage teamwork.

• Engage key stakeholders: build trusted relationships with clinicians, hospital administrators and industry partners.

If you’re looking to accelerate your medical device or biotech business with a partner who understands both the clinical and commercial sides of the industry, I would be honored to collaborate.